EXSERVAN™ (riluzole) oral film has the same dosing schedule as the
tablet form of riluzole:
Rectangular in shape, each oral film is individually packaged in a foil pouch.
Keep EXSERVAN™ in the foil pouch until you are ready to use. Check the expiration date printed on foil pouch before use and do not use if expired. Use right away after opening foil pouch. Make sure your hands are clean and dry, so the strip won’t stick to your fingers.
Do not drink liquid, chew, spit, or talk while EXSERVAN™ is dissolving. EXSERVAN™ oral films have a honey lemon flavor.
Then, swallow your saliva normally until the film has dissolved completely. The average time to dissolve is 2 minutes.
Do not use if you are allergic to riluzole or to any of its ingredients.
Before using EXSERVAN™, tell your doctor about all the medicines you take and all your health conditions, including if you:
EXSERVAN™ can cause serious side effects, including:
Liver Problems: Cases of liver injury, some fatal, have occurred in patients taking riluzole. Consult your doctor promptly if you experience unexplained nausea, vomiting, stomach (abdominal) pain, fatigue, weight loss (anorexia), jaundice (yellowing of the skin or whites of the eyes), and/or dark urine.
Low White Blood Cell Counts (Neutropenia): Tell your doctor if you develop a fever while taking EXSERVAN™.
Serious Lung Problems (Interstitial Lung Disease): Tell your doctor if you have problems with your lungs or breathing such as dry cough and difficult or labored breathing. Discontinue EXSERVAN™ immediately if you develop interstitial lung disease.
The most common side effects include numbness in the mouth or tongue, muscle weakness, nausea, lung problems, high blood pressure, and stomach (abdominal) pain.
These are not all the possible side effects of EXSERVAN™. Consult your doctor for medical advice about side effects.
To report side effects, contact Mitsubishi Tanabe Pharma America, Inc. at
Use EXSERVAN™ as prescribed. The recommended dosage for EXSERVAN™ is 50 mg taken orally twice daily at least 1 hour before or 2 hours after a meal. Place EXSERVAN™ oral film strip on the top of the tongue where it will adhere and dissolve. Swallow in a normal manner. Do not cut or split the film or take liquids with EXSERVAN™. Do not chew, spit, or talk while EXSERVAN™ is dissolving. Read the Instructions for Use for EXSERVAN™.
EXSERVAN™ (riluzole) is indicated for the treatment of amyotrophic lateral sclerosis (ALS).
Please click here to see the full Prescribing Information for EXSERVAN™.